Herein we describe a synthesis of (6R,12R)-6,12-dimethylpentadecan-2-one (5), the female produced sex pheromone of banded cucumber beetle Diabrotica balteata Le Conte, from (R)-4-methyl-delta-valerolactone, a methyl-branched chiron.
Shen W,Hao X,Shi Y,et al. Synthesis of (6R,12R)-6,12-Dimethylpentadecan-2-one, the Female-Produced Sex Pheromone from Banded Cucumber Beetle Diabrotica balteata, Based on a Chiron Approach[J]. Nat. Prod. Commun.,2015,10(12):2155-2160.