中国科学院上海有机化学研究所机构知识库
Advanced  
SIOC OpenIR  > 中科院有机氟化学重点实验室  > 期刊论文
学科主题: 氟化学
题名: Synthesis of diaryldifluoromethanes by Pd-catalyzed difluoroalkylation of arylboronic acids
其他题名: 通过钯催化芳基硼酸的二氟烷基化合成二芳基二氟甲烷
作者: Gu JW(顾继伟); Guo WH(郭文豪); Zhang XG(张新刚)
通讯作者: 张新刚
刊名: Org. Chem. Front.
发表日期: 2015
DOI: 10.1039/c4qo00246f
卷: 2, 期:1, 页:38-41
收录类别: SCI
文章类型: 论文
英文摘要: Diaryldifluoromethanes constitute a distinct class of fluorinated compounds in medicinal chemistry. But only limited methods to access this structural motif have been reported. Herein, we demonstrate the first example of Pd-catalyzed aryldifluoromethylation of arylboronic acids with readily available aryldifluoromethyl bromides. Because of its high efficiency, excellent functional group compatibility, and mild reaction conditions, this protocol provides a facile access to diaryldifluoromethanes. Preliminary mechanistic studies revealed that a Pd(0) L-n-initiated single electron transfer (SET) pathway is involved in the catalytic cycle.
语种: 英语
相关网址: 查看原文
WOS记录号: WOS:000364442500007
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/39755
Appears in Collections:中科院有机氟化学重点实验室_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
2015583.pdf(1035KB)期刊论文作者接受稿开放获取View Download

作者单位: 中科院上海有机化学研究所, 有机氟化学重点实验室

Recommended Citation:
Gu JW,Guo WH,Zhang XG. Synthesis of diaryldifluoromethanes by Pd-catalyzed difluoroalkylation of arylboronic acids[J]. Org. Chem. Front.,2015,2(1):38-41.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[顾继伟]'s Articles
[郭文豪]'s Articles
[张新刚]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[顾继伟]‘s Articles
[郭文豪]‘s Articles
[张新刚]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: 2015583.pdf
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace