SIOC OpenIR  > 中科院有机氟化学重点实验室
Recent Advances in C-H Trifluoromethylthiolation and Trifluoromethoxylation Reactions
Alternative Title碳氢键三氟甲硫基化与三氟甲氧基化的最新进展
Lin JH(林锦鸿); Ji YL(季云龙); Xiao JC(肖吉昌)
Source PublicationCurr. Org. Chem.
AbstractAs both trifluoromethylthio (CF3S) and trifluoromethoxy (CF3O) moieties have proved to be valuable functionalities in pharmaceutical chemistry, trifluoromethylthiolation and trifluoromethoxylation have received a great deal of attention. For the trifluoromethylthiolation reaction, a variety of efficient methods have been developed. Among these methods, C-H trifluoromethylthiolation avoids the need to prefunctionalize substrates, meaning that this straightforward protocol is quite attractive and promising. The first section of this review summarizes recent advances in this field, including Csp(3)-H, Csp(2)-H and Csp-H trifluoromethylthiolation and the asymmetric Csp(3)-H trifluoromethylthiolation reactions. Trifluoromethoxylation with safe trifluoromethoxylation reagents remains a significant challenge. The second section of this review summarizes the recent progress in trifluoromethoxylation reaction.
Subject Area氟化学
Indexed BySCI
WOS IDWOS:000358962300003
Citation statistics
Document Type期刊论文
Corresponding AuthorLin JH(林锦鸿); Xiao JC(肖吉昌)
Affiliation中科院上海有机化学研究所, 有机氟化学重点实验室
Recommended Citation
GB/T 7714
Lin JH,Ji YL,Xiao JC. Recent Advances in C-H Trifluoromethylthiolation and Trifluoromethoxylation Reactions[J]. Curr. Org. Chem.,2015,19(16):1541-1553.
APA 林锦鸿,季云龙,&肖吉昌.(2015).Recent Advances in C-H Trifluoromethylthiolation and Trifluoromethoxylation Reactions.Curr. Org. Chem.,19(16),1541-1553.
MLA 林锦鸿,et al."Recent Advances in C-H Trifluoromethylthiolation and Trifluoromethoxylation Reactions".Curr. Org. Chem. 19.16(2015):1541-1553.
Files in This Item:
File Name/Size DocType Version Access License
2015410.pdf(406KB)期刊论文作者接受稿开放获取CC BY-NC-SAApplication Full Text
Related Services
Recommend this item
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[林锦鸿]'s Articles
[季云龙]'s Articles
[肖吉昌]'s Articles
Baidu academic
Similar articles in Baidu academic
[林锦鸿]'s Articles
[季云龙]'s Articles
[肖吉昌]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[林锦鸿]'s Articles
[季云龙]'s Articles
[肖吉昌]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.