| Facile Access to Fluoromethylated Arenes by Nickel-Catalyzed Cross-Coupling between Arylboronic Acids and Fluoromethyl Bromide |
其他题名 | 镍催化下芳基硼酸与氟溴甲烷的偶联反应
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| An L(安伦); Xiao YL(肖玉兰); Min QQ(闵巧桥); Zhang XG(张新刚)
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| 2015
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发表期刊 | Angew. Chem.-Int. Edit.
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卷号 | 54期号:31页码:9079-9083 |
摘要 | The nickel-catalyzed fluoromethylation of arylboronic acids was achieved with the industrial raw material fluoromethyl bromide (CH2FBr) as the coupling partner. The reaction proceeded under mild reaction conditions with high efficiency; it features the use of a low-cost nickel catalyst, synthetic simplicity, and excellent functional-group compatibility, and provides facile access to fluoromethylated biologically relevant molecules. Preliminary mechanistic studies showed that a single-electron-transfer (SET) pathway is involved in the catalytic cycle. |
文章类型 | 论文
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学科领域 | 氟化学
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DOI | 10.1002/anie.201502882
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URL | 查看原文
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收录类别 | SCI
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语种 | 英语
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WOS记录号 | WOS:000358501500038
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引用统计 |
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文献类型 | 期刊论文
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条目标识符 | http://ir.sioc.ac.cn/handle/331003/39734
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专题 | 中科院有机氟化学重点实验室
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通讯作者 | Zhang XG(张新刚) |
作者单位 | 中科院上海有机化学研究所, 有机氟化学重点实验室
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推荐引用方式 GB/T 7714 |
An L,Xiao YL,Min QQ,et al. Facile Access to Fluoromethylated Arenes by Nickel-Catalyzed Cross-Coupling between Arylboronic Acids and Fluoromethyl Bromide[J]. Angew. Chem.-Int. Edit.,2015,54(31):9079-9083.
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APA |
安伦,肖玉兰,闵巧桥,&张新刚.(2015).Facile Access to Fluoromethylated Arenes by Nickel-Catalyzed Cross-Coupling between Arylboronic Acids and Fluoromethyl Bromide.Angew. Chem.-Int. Edit.,54(31),9079-9083.
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MLA |
安伦,et al."Facile Access to Fluoromethylated Arenes by Nickel-Catalyzed Cross-Coupling between Arylboronic Acids and Fluoromethyl Bromide".Angew. Chem.-Int. Edit. 54.31(2015):9079-9083.
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