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Direct and Convenient Mass Spectrometry Sampling with Ambient Flame Ionization
Alternative Title基于常压火焰离子化的直接和方便的质谱采样分析
Liu XP(刘小潘)1; Wang HY(王昊阳)1; Zhang JT(张骏婷)1; Wu MQ(吴梦茜)1; Qi WS(祁婉舒)1; Zhu H(朱晖)1; Guo YL(郭寅龙)1
Source PublicationSci Rep
AbstractRecent innovations in ambient ionization technology for the direct analysis of various samples in their native environment facilitate the development and applications of mass spectrometry in natural science. Presented here is a novel, convenient and flame-based ambient ionization method for mass spectrometric analysis of organic compounds, termed as the ambient flame ionization (AFI) ion source. The key features of AFI ion source were no requirement of (high) voltages, laser beams and spray gases, but just using small size of n-butane flame (height approximately 1 cm, about 500 degrees C) to accomplish the rapid desorption and ionization for direct analysis of gaseous-, liquid-and solid-phase organic compounds, as well as real-world samples. This method has high sensitivity with a limit of detection of 1 picogram for propyphenazone, which allows consuming trace amount of samples. Compared to previous ionization methods, this ion source device is extremely simple, maintain-free, low-cost, user-friendly so that even an ordinary lighter (with n-butane as fuel) can achieve efficient ionization. A new orientation to mass spectrometry ion source exploitation might emerge from such a convenient, easy and inexpensive AFI ion source.
Subject Area分析化学
Indexed BySCI
WOS IDWOS:000364945400001
Citation statistics
Cited Times:10[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Corresponding AuthorWang HY(王昊阳); Guo YL(郭寅龙)
Affiliation1.中科院上海有机化学研究所, 金属有机化学国家重点实验室
2.中科院上海有机化学研究所, 上海质谱中心
Recommended Citation
GB/T 7714
Liu XP,Wang HY,Zhang JT,et al. Direct and Convenient Mass Spectrometry Sampling with Ambient Flame Ionization[J]. Sci Rep,2015,5:16893.
APA 刘小潘.,王昊阳.,张骏婷.,吴梦茜.,祁婉舒.,...&郭寅龙.(2015).Direct and Convenient Mass Spectrometry Sampling with Ambient Flame Ionization.Sci Rep,5,16893.
MLA 刘小潘,et al."Direct and Convenient Mass Spectrometry Sampling with Ambient Flame Ionization".Sci Rep 5(2015):16893.
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