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Synthesis of Multiple-Substituted Pyrroles via Gold(I)-Catalyzed Hydroamination/Cyclization Cascade
Alternative Title金催化氢氨化/环化串联反应: 多取代吡咯的合成
Li XD(李向东); Chen M(陈铭); Jie X(解鑫); Sun N(孙宁); Li S(李石); Liu YH(刘元红)
2015
Source PublicationOrg. Lett.
Volume17Issue:12Pages:2984-2987
AbstractA gold-catalyzed cascade hydroamination/cyclization reaction of alpha-amino ketones with alkynes to form substituted pyrroles has been developed. The method offers several advantages such as high regioselectivity with the tested cases, wide functional group tolerance, and easily accessible starting materials. The synthetic utility of the obtained pyrrole products was demonstrated by their efficient transformations to 2-vinylated pyrroles via gold-catalyzed intermolecular hydroarylation.
Subtype论文
Subject Area金属有机化学
DOI10.1021/acs.orglett.5b01281
URL查看原文
Indexed BySCI
Language英语
WOS IDWOS:000356845000031
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Document Type期刊论文
Identifierhttp://ir.sioc.ac.cn/handle/331003/39614
Collection金属有机化学国家重点实验室
Corresponding AuthorLi S(李石); Liu YH(刘元红)
Affiliation中科院上海有机化学研究所, 金属有机化学国家重点实验室
Recommended Citation
GB/T 7714
Li XD,Chen M,Jie X,et al. Synthesis of Multiple-Substituted Pyrroles via Gold(I)-Catalyzed Hydroamination/Cyclization Cascade[J]. Org. Lett.,2015,17(12):2984-2987.
APA 李向东,陈铭,解鑫,孙宁,李石,&刘元红.(2015).Synthesis of Multiple-Substituted Pyrroles via Gold(I)-Catalyzed Hydroamination/Cyclization Cascade.Org. Lett.,17(12),2984-2987.
MLA 李向东,et al."Synthesis of Multiple-Substituted Pyrroles via Gold(I)-Catalyzed Hydroamination/Cyclization Cascade".Org. Lett. 17.12(2015):2984-2987.
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