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Palladium-catalyzed highly efficient synthesis of functionalized indolizines via cross-coupling/cycloisomerization cascade
Alternative Title钯催化的交叉偶联/环异构化串联反应: 官能团化中氮茚的高效合成
Zhang LW(张良伟)1; Li XD(李向东)1; Liu YH(刘元红)1; Zhang DY(张大永)1
2015
Source PublicationChem. Commun.
Volume51Issue:30Pages:6633-6636
AbstractAn efficient Pd-catalyzed cross-coupling/cycloisomerization of 3-(2-pyridyl) propargyl carbonates with organoboronic acids has been developed, which provides a straightforward route for the synthesis of 1,3-disubstituted indolizines with a wide variety of substituents. The mechanistic study indicates that the reaction proceeds via formation of an allenyl pyridine intermediate through palladium-catalyzed coupling reaction followed by cyclization.
Subtype论文
Subject Area金属有机化学
DOI10.1039/c5cc01151e
URL查看原文
Indexed BySCI
Language英语
WOS IDWOS:000352269000041
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Document Type期刊论文
Identifierhttp://ir.sioc.ac.cn/handle/331003/39594
Collection金属有机化学国家重点实验室
Corresponding AuthorLiu YH(刘元红); Zhang DY(张大永)
Affiliation1.中国药科大学
2.中科院上海有机化学研究所, 金属有机化学国家重点实验室
Recommended Citation
GB/T 7714
Zhang LW,Li XD,Liu YH,et al. Palladium-catalyzed highly efficient synthesis of functionalized indolizines via cross-coupling/cycloisomerization cascade[J]. Chem. Commun.,2015,51(30):6633-6636.
APA 张良伟,李向东,刘元红,&张大永.(2015).Palladium-catalyzed highly efficient synthesis of functionalized indolizines via cross-coupling/cycloisomerization cascade.Chem. Commun.,51(30),6633-6636.
MLA 张良伟,et al."Palladium-catalyzed highly efficient synthesis of functionalized indolizines via cross-coupling/cycloisomerization cascade".Chem. Commun. 51.30(2015):6633-6636.
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