| Total Synthesis of Epoxyeujindole A | |
| Alternative Title | Total Synthesis of Epoxyeujindole A |
| Lu ZH(陆钊洪); Li HL(李海龙); Bian M(卞明); Li A(李昂) | |
| 2015 | |
| Source Publication | J. Am. Chem. Soc.
 |
| Volume | 137Issue:43Pages:13764-13767 |
| Abstract | The total synthesis of epoxyeujindole A, a structurally unusual indole diterpenoid isolated from Eupenicillium javanicum, has been accomplished for the first time. The synthesis features a late-stage cationic cyclization strategy, which took advantage of an electron-rich olefinic substrate. The CDE ring system was assembled via an enantioselective conjugate addition/alkylation, a Luche cyclization, and a Nozaki-Hiyama-Kishi reaction. The heavily substituted A ring was constructed through a Suzuki-Miyaura coupling and a cationic cyclization, and the bridged fused B ring was formed through a Prins reaction. |
| Subtype | 论文 |
| Subject Area | 生命有机化学 |
| DOI | 10.1021/jacs.5b09198 |
| URL | 查看原文 |
| Indexed By | SCI |
| Language | 英语 |
| WOS ID | WOS:000364355900011 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.sioc.ac.cn/handle/331003/39536 |
| Collection | 生命有机化学国家重点实验室 |
| Corresponding Author | Li A(李昂) |
| Affiliation | 中科院上海有机化学研究所, 生命有机化学国家重点实验室 |
| Recommended Citation GB/T 7714 | Lu ZH,Li HL,Bian M,et al. Total Synthesis of Epoxyeujindole A[J]. J. Am. Chem. Soc.,2015,137(43):13764-13767. |
| APA | 陆钊洪,李海龙,卞明,&李昂.(2015).Total Synthesis of Epoxyeujindole A.J. Am. Chem. Soc.,137(43),13764-13767. |
| MLA | 陆钊洪,et al."Total Synthesis of Epoxyeujindole A".J. Am. Chem. Soc. 137.43(2015):13764-13767. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| 2015569.pdf（942KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | Application Full Text | |
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