Total Synthesis of Epoxyeujindole A

doi:10.1021/jacs.5b09198

	Total Synthesis of Epoxyeujindole A
其他题名	Total Synthesis of Epoxyeujindole A
	Lu ZH(陆钊洪); Li HL(李海龙); Bian M(卞明); Li A(李昂)
	2015
发表期刊	J. Am. Chem. Soc.
卷号	137 期号:43 页码:13764-13767
摘要	The total synthesis of epoxyeujindole A, a structurally unusual indole diterpenoid isolated from Eupenicillium javanicum, has been accomplished for the first time. The synthesis features a late-stage cationic cyclization strategy, which took advantage of an electron-rich olefinic substrate. The CDE ring system was assembled via an enantioselective conjugate addition/alkylation, a Luche cyclization, and a Nozaki-Hiyama-Kishi reaction. The heavily substituted A ring was constructed through a Suzuki-Miyaura coupling and a cationic cyclization, and the bridged fused B ring was formed through a Prins reaction.
文章类型	论文
学科领域	生命有机化学
DOI	10.1021/jacs.5b09198
URL	查看原文
收录类别	SCI
语种	英语
WOS记录号	WOS:000364355900011
引用统计	被引频次：19[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.sioc.ac.cn/handle/331003/39536
专题	生命有机化学国家重点实验室
通讯作者	Li A(李昂)
作者单位	中科院上海有机化学研究所, 生命有机化学国家重点实验室
推荐引用方式 GB/T 7714	Lu ZH,Li HL,Bian M,et al. Total Synthesis of Epoxyeujindole A[J]. J. Am. Chem. Soc.,2015,137(43):13764-13767.
APA	陆钊洪,李海龙,卞明,&李昂.(2015).Total Synthesis of Epoxyeujindole A.J. Am. Chem. Soc.,137(43),13764-13767.
MLA	陆钊洪,et al."Total Synthesis of Epoxyeujindole A".J. Am. Chem. Soc. 137.43(2015):13764-13767.

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2015569.pdf（942KB）	期刊论文	作者接受稿	开放获取	CC BY-NC-SA	请求全文