SIOC OpenIR  > 生命有机化学国家重点实验室
Total Synthesis of Epoxyeujindole A
Alternative TitleTotal Synthesis of Epoxyeujindole A
Lu ZH(陆钊洪); Li HL(李海龙); Bian M(卞明); Li A(李昂)
Source PublicationJ. Am. Chem. Soc.
AbstractThe total synthesis of epoxyeujindole A, a structurally unusual indole diterpenoid isolated from Eupenicillium javanicum, has been accomplished for the first time. The synthesis features a late-stage cationic cyclization strategy, which took advantage of an electron-rich olefinic substrate. The CDE ring system was assembled via an enantioselective conjugate addition/alkylation, a Luche cyclization, and a Nozaki-Hiyama-Kishi reaction. The heavily substituted A ring was constructed through a Suzuki-Miyaura coupling and a cationic cyclization, and the bridged fused B ring was formed through a Prins reaction.
Subject Area生命有机化学
Indexed BySCI
WOS IDWOS:000364355900011
Citation statistics
Cited Times:23[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Corresponding AuthorLi A(李昂)
Affiliation中科院上海有机化学研究所, 生命有机化学国家重点实验室
Recommended Citation
GB/T 7714
Lu ZH,Li HL,Bian M,et al. Total Synthesis of Epoxyeujindole A[J]. J. Am. Chem. Soc.,2015,137(43):13764-13767.
APA 陆钊洪,李海龙,卞明,&李昂.(2015).Total Synthesis of Epoxyeujindole A.J. Am. Chem. Soc.,137(43),13764-13767.
MLA 陆钊洪,et al."Total Synthesis of Epoxyeujindole A".J. Am. Chem. Soc. 137.43(2015):13764-13767.
Files in This Item:
File Name/Size DocType Version Access License
2015569.pdf(942KB)期刊论文作者接受稿开放获取CC BY-NC-SAApplication Full Text
Related Services
Recommend this item
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[陆钊洪]'s Articles
[李海龙]'s Articles
[卞明]'s Articles
Baidu academic
Similar articles in Baidu academic
[陆钊洪]'s Articles
[李海龙]'s Articles
[卞明]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[陆钊洪]'s Articles
[李海龙]'s Articles
[卞明]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.