| Total Synthesis of Epoxyeujindole A |
其他题名 | Total Synthesis of Epoxyeujindole A
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| Lu ZH(陆钊洪); Li HL(李海龙); Bian M(卞明); Li A(李昂)
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| 2015
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发表期刊 | J. Am. Chem. Soc.
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卷号 | 137期号:43页码:13764-13767 |
摘要 | The total synthesis of epoxyeujindole A, a structurally unusual indole diterpenoid isolated from Eupenicillium javanicum, has been accomplished for the first time. The synthesis features a late-stage cationic cyclization strategy, which took advantage of an electron-rich olefinic substrate. The CDE ring system was assembled via an enantioselective conjugate addition/alkylation, a Luche cyclization, and a Nozaki-Hiyama-Kishi reaction. The heavily substituted A ring was constructed through a Suzuki-Miyaura coupling and a cationic cyclization, and the bridged fused B ring was formed through a Prins reaction. |
文章类型 | 论文
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学科领域 | 生命有机化学
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DOI | 10.1021/jacs.5b09198
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URL | 查看原文
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收录类别 | SCI
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语种 | 英语
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WOS记录号 | WOS:000364355900011
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引用统计 |
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文献类型 | 期刊论文
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条目标识符 | http://ir.sioc.ac.cn/handle/331003/39536
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专题 | 生命有机化学国家重点实验室
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通讯作者 | Li A(李昂) |
作者单位 | 中科院上海有机化学研究所, 生命有机化学国家重点实验室
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推荐引用方式 GB/T 7714 |
Lu ZH,Li HL,Bian M,et al. Total Synthesis of Epoxyeujindole A[J]. J. Am. Chem. Soc.,2015,137(43):13764-13767.
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APA |
陆钊洪,李海龙,卞明,&李昂.(2015).Total Synthesis of Epoxyeujindole A.J. Am. Chem. Soc.,137(43),13764-13767.
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MLA |
陆钊洪,et al."Total Synthesis of Epoxyeujindole A".J. Am. Chem. Soc. 137.43(2015):13764-13767.
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