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Synthesis of the ABC skeleton of the aglycon of Echinoside A
Alternative TitleEchinoside A甙元ABC环骨架的合成
Yu J(余军)1; Yu B(俞飚)1
Source PublicationChin. Chem. Lett.
AbstractEchinoside A is a triterpene saponin isolated from the sea cucumber Actinopyga echinites (JAEGER), which displays potent antitumor activities in vitro and in vivo. Here, we report the synthesis of the ABC-fused ring skeleton of the aglycon of Echinoside A, with the enantiomerically pure (+)-Wieland-Miescher ketone being used as starting material and a Robinson annulation as the key reaction. (C) 2015 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
Subject Area生命有机化学
Indexed BySCI
WOS IDWOS:000364269700001
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Document Type期刊论文
Corresponding AuthorYu J(余军); Yu B(俞飚)
2.中科院上海有机化学研究所, 生命有机化学国家重点实验室
Recommended Citation
GB/T 7714
Yu J,Yu B. Synthesis of the ABC skeleton of the aglycon of Echinoside A[J]. Chin. Chem. Lett.,2015,26(11):1331-1335.
APA 余军,&俞飚.(2015).Synthesis of the ABC skeleton of the aglycon of Echinoside A.Chin. Chem. Lett.,26(11),1331-1335.
MLA 余军,et al."Synthesis of the ABC skeleton of the aglycon of Echinoside A".Chin. Chem. Lett. 26.11(2015):1331-1335.
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