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学科主题: 生命有机化学
题名: Synthesis of the ABC skeleton of the aglycon of Echinoside A
其他题名: Echinoside A甙元ABC环骨架的合成
作者: Yu J(余军)1; Yu B(俞飚)1
通讯作者: 余军 ; 俞飚
刊名: Chin. Chem. Lett.
发表日期: 2015
DOI: 10.1016/j.cclet.2015.08.010
卷: 26, 期:11, 页:1331-1335
收录类别: SCI
文章类型: 论文
英文摘要: Echinoside A is a triterpene saponin isolated from the sea cucumber Actinopyga echinites (JAEGER), which displays potent antitumor activities in vitro and in vivo. Here, we report the synthesis of the ABC-fused ring skeleton of the aglycon of Echinoside A, with the enantiomerically pure (+)-Wieland-Miescher ketone being used as starting material and a Robinson annulation as the key reaction. (C) 2015 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
语种: 英语
相关网址: 查看原文
WOS记录号: WOS:000364269700001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/39533
Appears in Collections:生命有机化学国家重点实验室_期刊论文

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作者单位: 1.中国科学技术大学
2.中科院上海有机化学研究所, 生命有机化学国家重点实验室

Recommended Citation:
Yu J,Yu B. Synthesis of the ABC skeleton of the aglycon of Echinoside A[J]. Chin. Chem. Lett.,2015,26(11):1331-1335.
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