Efficient synthesis of pyrrolo[2,3-d]pyrimidines via a Cu(I)/6-methylpicolinic acid catalyzed coupling reaction

doi:10.1016/j.tetlet.2014.12.098

	Efficient synthesis of pyrrolo[2,3-d]pyrimidines via a Cu(I)/6-methylpicolinic acid catalyzed coupling reaction
其他题名	铜(I)/6-甲基-哌啶-2-羧酸催化的偶联反应合成吡咯并嘧啶化合物
	Jiang X(蒋西)1; Sun DQ(孙德群)1; Jiang YW(蒋咏文)1; Ma DW(马大为)1
	2015
发表期刊	Tetrahedron Lett.
卷号	56 期号:23 页码:3259-3261
摘要	Copper/6-methylpicolinic acid catalyzed coupling reaction of substituted 5-bromopyrimidin-4-amines with alkynes and subsequent cyclization took place in DMSO at 100-110 degrees C to afford 2-chloro-pyrrolo [2,3-d]pyrimidines in moderate to excellent yields. Variable functional groups, including aromatic and aliphatic groups, could be introduced at the 6 and 7 positions using this method. (C) 2014 Elsevier Ltd. All rights reserved.
文章类型	论文
学科领域	生命有机化学
DOI	10.1016/j.tetlet.2014.12.098
URL	查看原文
收录类别	SCI
语种	英语
WOS记录号	WOS:000356544800071
引用统计	被引频次：6[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.sioc.ac.cn/handle/331003/39511
专题	生命有机化学国家重点实验室
通讯作者	Jiang YW(蒋咏文); Ma DW(马大为)
作者单位	1.山东大学威海分校 2.中科院上海有机化学研究所, 生命有机化学国家重点实验室
推荐引用方式 GB/T 7714	Jiang X,Sun DQ,Jiang YW,et al. Efficient synthesis of pyrrolo[2,3-d]pyrimidines via a Cu(I)/6-methylpicolinic acid catalyzed coupling reaction[J]. Tetrahedron Lett.,2015,56(23):3259-3261.
APA	蒋西,孙德群,蒋咏文,&马大为.(2015).Efficient synthesis of pyrrolo[2,3-d]pyrimidines via a Cu(I)/6-methylpicolinic acid catalyzed coupling reaction.Tetrahedron Lett.,56(23),3259-3261.
MLA	蒋西,et al."Efficient synthesis of pyrrolo[2,3-d]pyrimidines via a Cu(I)/6-methylpicolinic acid catalyzed coupling reaction".Tetrahedron Lett. 56.23(2015):3259-3261.