| Asymmetric Total Synthesis of Mycoleptodiscin A |
其他题名 | Asymmetric Total Synthesis of Mycoleptodiscin A
|
| Zhou SP(周述鹏); Chen H(陈浩); Luo YJ(罗乙杰); Zhang WH(张纹豪); Li A(李昂)
|
| 2015
|
发表期刊 | Angew. Chem.-Int. Edit.
 |
卷号 | 54期号:23页码:6878-6882 |
摘要 | The first total synthesis of mycoleptodiscinA, a structurally unusual indolosesquiterpenoid possessing an ortho-benzoquinone motif, has been accomplished. A sulfone alkylation coupled two readily available fragments to give an aryl triene intermediate. The tetracyclic core of the molecule was assembled through a highly enantioselective iridium-catalyzed polyene cyclization. The benzylic homologation was achieved by a cationic cyanation. The indole motif was constructed via a copper-mediated intramolecular CN bond formation at a late stage. |
文章类型 | 论文
|
学科领域 | 生命有机化学
|
DOI | 10.1002/anie.201501021
|
URL | 查看原文
|
收录类别 | SCI
|
语种 | 英语
|
WOS记录号 | WOS:000355314100036
|
引用统计 |
|
文献类型 | 期刊论文
|
条目标识符 | http://ir.sioc.ac.cn/handle/331003/39505
|
专题 | 生命有机化学国家重点实验室
|
通讯作者 | Li A(李昂) |
作者单位 | 中科院上海有机化学研究所, 生命有机化学国家重点实验室
|
推荐引用方式 GB/T 7714 |
Zhou SP,Chen H,Luo YJ,et al. Asymmetric Total Synthesis of Mycoleptodiscin A[J]. Angew. Chem.-Int. Edit.,2015,54(23):6878-6882.
|
APA |
周述鹏,陈浩,罗乙杰,张纹豪,&李昂.(2015).Asymmetric Total Synthesis of Mycoleptodiscin A.Angew. Chem.-Int. Edit.,54(23),6878-6882.
|
MLA |
周述鹏,et al."Asymmetric Total Synthesis of Mycoleptodiscin A".Angew. Chem.-Int. Edit. 54.23(2015):6878-6882.
|
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论