中国科学院上海有机化学研究所机构知识库
Advanced  
SIOC OpenIR  > 金属有机化学国家重点实验室  > 期刊论文
学科主题: 金属有机化学
题名: Remote Ester Groups Switch Selectivity: Diastereodivergent Synthesis of Tetracyclic Spiroindolines
其他题名: 远程酯基调控选择性: 非对映选择性合成四环螺环吲哚啉
作者: Zhu J(朱俊)1; Liang Y(梁勇)1; Wang LJ(王丽佳)1; Zheng ZB(郑中博)1; HOUK K N1; Tang Y(唐勇)1
通讯作者: 唐勇
刊名: J. Am. Chem. Soc.
发表日期: 2014
DOI: 10.1021/ja503117q
卷: 136, 期:19, 页:6900-6903
收录类别: SCI
英文摘要: Stereocontrol in the synthesis of structurally complex molecules, especially those with all-carbon quaternary stereocenters, remains a challenge. Here, we reported the preparation of a class of tetracyclic cyclopenta-fused spiroindoline skeletons through Cu(II)catalyzed intramolecular [3 + 2] annulation reactions of donor-acceptor cyclopropanes with indoles. Both cis- and trans-diastereomers of tetracyclic spiroindolines are accessed with high selectivities by altering the remote ester groups of cyclopropanes. The origins of this stereocontrol are identified using DFT calculations: attractive interactions between the ester group and arene favor the generation of the trans isomer, while the formation of the cis isomer is preferred when steric repulsions become predominant.
语种: 英语
相关网址: 查看原文
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/39064
Appears in Collections:金属有机化学国家重点实验室_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
2014242.pdf(845KB)期刊论文作者接受稿开放获取View Download

作者单位: 1.中科院上海有机化学研究所
2.美国加州大学洛杉矶分校

Recommended Citation:
Zhu J,Liang Y,Wang LJ,et al. Remote Ester Groups Switch Selectivity: Diastereodivergent Synthesis of Tetracyclic Spiroindolines[J]. J. Am. Chem. Soc.,2014,136(19):6900-6903.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[朱俊]'s Articles
[梁勇]'s Articles
[王丽佳]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[朱俊]‘s Articles
[梁勇]‘s Articles
[王丽佳]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: 2014242.pdf
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace