SIOC OpenIR  > 金属有机化学国家重点实验室
Titanium-mediated cross-coupling reactions of 1,3-butadiynes with α-iminonitriles to 3-aminopyrroles: observation of an imino aza-Nazarov cyclization
其他题名钛促进的1,3-共轭双炔与氰基亚胺的交叉偶联反应: 通过imino-aza-Nazarov型环化合成3-氨基吡咯衍生物
You X(尤旭); Jie X(解鑫); Sun RH(孙仁红); Chen HY(陈好益); Li S(李石); Liu YH(刘元红)
2014
发表期刊Org. Chem. Front.
卷号1页码:940-946
摘要Ti(OiPr)4/2 nBuLi-mediated highly efficient cross-coupling reactions of 1,3-butadiynes with α-iminonitriles are described. The method provides convenient access to functionalized 3-aminopyrroles with a wide diversity of substituents in a highly regioselective manner. When optically pure α-iminonitrile is employed in this reaction, a chiral pyrrole derivative is obtained without loss of enantiopurity. Mechanistic study indicates that the 3-aminopyrroles are formed upon treatment of the crude hydrolysis products with silica gel or Lewis acid. A novel imino aza-Nazarov cyclization reaction is proposed to account for the formation of the pyrrole products. Employing the titanium-monoyne complex in this reaction resulted in the homocoupling of α-iminonitriles, leading to the formation of 1,2-diimines.
学科领域金属有机化学
DOI10.1039/c4qo00159a
URL查看原文
语种英语
引用统计
文献类型期刊论文
条目标识符http://ir.sioc.ac.cn/handle/331003/39014
专题金属有机化学国家重点实验室
通讯作者Liu YH(刘元红)
作者单位中科院上海有机化学研究所
推荐引用方式
GB/T 7714
You X,Jie X,Sun RH,et al. Titanium-mediated cross-coupling reactions of 1,3-butadiynes with α-iminonitriles to 3-aminopyrroles: observation of an imino aza-Nazarov cyclization[J]. Org. Chem. Front.,2014,1:940-946.
APA 尤旭,解鑫,孙仁红,陈好益,李石,&刘元红.(2014).Titanium-mediated cross-coupling reactions of 1,3-butadiynes with α-iminonitriles to 3-aminopyrroles: observation of an imino aza-Nazarov cyclization.Org. Chem. Front.,1,940-946.
MLA 尤旭,et al."Titanium-mediated cross-coupling reactions of 1,3-butadiynes with α-iminonitriles to 3-aminopyrroles: observation of an imino aza-Nazarov cyclization".Org. Chem. Front. 1(2014):940-946.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
2014041.pdf(592KB)期刊论文作者接受稿开放获取CC BY-NC-SA请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[尤旭]的文章
[解鑫]的文章
[孙仁红]的文章
百度学术
百度学术中相似的文章
[尤旭]的文章
[解鑫]的文章
[孙仁红]的文章
必应学术
必应学术中相似的文章
[尤旭]的文章
[解鑫]的文章
[孙仁红]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。