SIOC OpenIR  > 金属有机化学国家重点实验室
Enantioselective Double Manipulation of Tetrahydroisoquinolines with Terminal Alkynes and Aldehydes under Copper(I) Catalysis
Alternative Title铜(I)催化的对映选择性的四氢异喹啉、末端炔和醛的反应
Lin WL(林渭龙)1; Cao T(曹陶)1; Fan W(范武)1; Han YL(韩玉林)1; Kuang JQ(况锦强)1; Luo HW(罗鸿文)1; 缪不可言1; Tang XJ(汤鑫军)1; Yu Q(俞琼)1; Yuan WM(袁伟民)1; Zhang JS(张加生)1; Zhu C(朱灿)1; Ma SM(麻生明)1
2014
Source PublicationAngew. Chem.-Int. Edit.
Volume53Issue:1Pages:277-281
AbstractTetrahydroisoquinoline alkaloids with a C1 stereogenic center are a common unit in many natural and non-natural compounds of biological importance. Herein we describe a novel Cu-I-catalyzed highly chemo- and enantioselective synthesis of chiral tetrahydroisoquinoline-alkaloid derivatives from readily available unsubstituted tetrahydroisoquinolines, aldehydes, and terminal alkynes in the presence of the ligand (R,R)-N-pinap. This synthetic operation installs two substituents in the 1- and 2-positions.
Subject Area金属有机化学
DOI10.1002/anie.201308699
URL查看原文
Indexed BySCI
Language英语
Citation statistics
Cited Times:87[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sioc.ac.cn/handle/331003/39010
Collection金属有机化学国家重点实验室
Corresponding AuthorMa SM(麻生明)
Affiliation1.中科院上海有机化学研究所
2.华东师范大学
Recommended Citation
GB/T 7714
Lin WL,Cao T,Fan W,et al. Enantioselective Double Manipulation of Tetrahydroisoquinolines with Terminal Alkynes and Aldehydes under Copper(I) Catalysis[J]. Angew. Chem.-Int. Edit.,2014,53(1):277-281.
APA 林渭龙.,曹陶.,范武.,韩玉林.,况锦强.,...&麻生明.(2014).Enantioselective Double Manipulation of Tetrahydroisoquinolines with Terminal Alkynes and Aldehydes under Copper(I) Catalysis.Angew. Chem.-Int. Edit.,53(1),277-281.
MLA 林渭龙,et al."Enantioselective Double Manipulation of Tetrahydroisoquinolines with Terminal Alkynes and Aldehydes under Copper(I) Catalysis".Angew. Chem.-Int. Edit. 53.1(2014):277-281.
Files in This Item:
File Name/Size DocType Version Access License
2014031.pdf(435KB)期刊论文作者接受稿开放获取CC BY-NC-SAApplication Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[林渭龙]'s Articles
[曹陶]'s Articles
[范武]'s Articles
Baidu academic
Similar articles in Baidu academic
[林渭龙]'s Articles
[曹陶]'s Articles
[范武]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[林渭龙]'s Articles
[曹陶]'s Articles
[范武]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.