SIOC OpenIR  > 生命有机化学国家重点实验室
Total synthesis of ent-(-)-azonazine using a biomimetic direct oxidative cyclization and structural reassignment of natural product
其他题名Total synthesis of ent-(-)-azonazine using a biomimetic direct oxidative cyclization and structural reassignment of natural product
Zhao JC(赵吉辰); Yu SM(于顺明); Qiu HB(邱海波); Yao ZJ(姚祝军)
2014
发表期刊Tetrahedron
卷号70期号:19页码:3197-3210
摘要A biomimetic approach has been investigated and developed for the total synthesis of azonazine, an unusual marine natural cyclopeptide containing a rigid transannular 10-membered ring. A hypervalent iodine-mediated direct oxidative cyclization was successfully developed and applied to construct the highly strained core, which was the key step in the first total synthesis of ent-(-)-azonazine. Based on the physical evidences of synthesized diastereomer and enantiomer of azonazine, both the relative and absolute configurations of the natural product were revised. Two fluorinated azonazine derivatives were also synthesized in short convenient steps utilizing the same intermediate in this work. The established total synthesis opens a potential opportunity to study the structure activity relationship of natural azonazine. (c) 2014 Elsevier Ltd. All rights reserved.
学科领域生命有机化学
DOI10.1016/j.tet.2014.03.061
URL查看原文
收录类别SCI
语种英语
引用统计
被引频次:8[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.sioc.ac.cn/handle/331003/38942
专题生命有机化学国家重点实验室
通讯作者Yao ZJ(姚祝军)
作者单位中科院上海有机化学研究所
推荐引用方式
GB/T 7714
Zhao JC,Yu SM,Qiu HB,et al. Total synthesis of ent-(-)-azonazine using a biomimetic direct oxidative cyclization and structural reassignment of natural product[J]. Tetrahedron,2014,70(19):3197-3210.
APA 赵吉辰,于顺明,邱海波,&姚祝军.(2014).Total synthesis of ent-(-)-azonazine using a biomimetic direct oxidative cyclization and structural reassignment of natural product.Tetrahedron,70(19),3197-3210.
MLA 赵吉辰,et al."Total synthesis of ent-(-)-azonazine using a biomimetic direct oxidative cyclization and structural reassignment of natural product".Tetrahedron 70.19(2014):3197-3210.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
2014199.pdf(1665KB)期刊论文作者接受稿开放获取CC BY-NC-SA请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[赵吉辰]的文章
[于顺明]的文章
[邱海波]的文章
百度学术
百度学术中相似的文章
[赵吉辰]的文章
[于顺明]的文章
[邱海波]的文章
必应学术
必应学术中相似的文章
[赵吉辰]的文章
[于顺明]的文章
[邱海波]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。