SIOC OpenIR  > 中科院有机氟化学重点实验室
Heteroaryldifluoromethylation of Organoborons Catalyzed by Palladium: Facile Access to Aryl(Heteroaryl)difluoromethanes
Alternative Title一种简便合成芳基(杂芳基)二氟甲烷的方法: 有机硼的杂芳基二氟甲基化
Xiao YL(肖玉兰); Zhang B(章博); Feng Z(冯璋); Zhang XG(张新刚)
2014
Source PublicationOrg. Lett.
Volume16Issue:18Pages:4822-4825
AbstractA first example of Pd-catalyzed heteroaryldifluoromethylation of organoborons with bromodifluoromethylated heteroarenes has been described. The use of phosphine ligand PAd(2)(n-Bu)center dot HI is critical for the reaction efficiency. With use of this ligand, a wide range of aryl(heteroaryl)difluoromethanes were obtained with high efficiency. The notable features of this reaction are its broad substrate scope and excellent functional group compatibility, thus providing a facile protocol for application in drug discovery and development.
Subject Area氟化学
DOI10.1021/ol502121m
URL查看原文
Indexed BySCI
Language英语
Citation statistics
Document Type期刊论文
Identifierhttp://ir.sioc.ac.cn/handle/331003/38881
Collection中科院有机氟化学重点实验室
Corresponding AuthorZhang XG(张新刚)
Affiliation中科院上海有机化学研究所
Recommended Citation
GB/T 7714
Xiao YL,Zhang B,Feng Z,et al. Heteroaryldifluoromethylation of Organoborons Catalyzed by Palladium: Facile Access to Aryl(Heteroaryl)difluoromethanes[J]. Org. Lett.,2014,16(18):4822-4825.
APA 肖玉兰,章博,冯璋,&张新刚.(2014).Heteroaryldifluoromethylation of Organoborons Catalyzed by Palladium: Facile Access to Aryl(Heteroaryl)difluoromethanes.Org. Lett.,16(18),4822-4825.
MLA 肖玉兰,et al."Heteroaryldifluoromethylation of Organoborons Catalyzed by Palladium: Facile Access to Aryl(Heteroaryl)difluoromethanes".Org. Lett. 16.18(2014):4822-4825.
Files in This Item:
File Name/Size DocType Version Access License
2014426.pdf(440KB)期刊论文作者接受稿开放获取CC BY-NC-SAApplication Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[肖玉兰]'s Articles
[章博]'s Articles
[冯璋]'s Articles
Baidu academic
Similar articles in Baidu academic
[肖玉兰]'s Articles
[章博]'s Articles
[冯璋]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[肖玉兰]'s Articles
[章博]'s Articles
[冯璋]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.