SIOC OpenIR  > 分析化学研究室
Solvent-Assisted Electrospray Ionization for Direct Analysis of Various Compounds (Complex) from Low/Nonpolar Solvents and Eluents
其他题名溶剂辅助电喷雾离子化方法的开发用于非/低极性溶剂中样本的直接检测
Zhang JT(张骏婷); Wang HY(王昊阳); Zhu W(朱微); Cai TT(蔡婷婷); Guo YL(郭寅龙)
2014
发表期刊Anal. Chem.
卷号86期号:18页码:8937-8942
摘要Electrospray ionization (ESI) is a powerful ionization technique with a wide range of applications. However, the analytes in low/nonpolar solvents cannot be analyzed directly in electrospray ionization-mass spectrometry (ESI-MS), because low/nonpolar solvents are incompatible with ESI, because of their low conductivity. To circumvent this problem, we introduce an electrospray-based ionization method termed solvent-assisted electrospray ionization (SAESI). With the help of electrospray solvents at the tip of the spray needle, compounds in non-electrospray ionization-friendly solvents can be ionized directly using solvent-assisted electrospray ionization-mass spectrometry (SAESI-MS). The key features that the assistant solvent can be chosen flexibly and makes little interference to samples lead to better ionization performance in detection of organic reaction intermediates and real-time analysis of polymers and chiral drugs separated by gel permeation chromatography (GPC) and normal phase liquid chromatography (NPLC). Furthermore, it can achieve online hydrogen/deuterium (H/D) exchange reaction and even mitigate the signal suppression caused by strong acid modifiers in liquid chromatography. In addition, all parts of this device are commercially available and it only requires two parameters to be optimized, which makes SAESI easy to handle.
学科领域分析化学
DOI10.1021/ac502656a
URL查看原文
收录类别SCI
语种英语
引用统计
文献类型期刊论文
条目标识符http://ir.sioc.ac.cn/handle/331003/38595
专题分析化学研究室
通讯作者Wang HY(王昊阳); Guo YL(郭寅龙)
作者单位中科院上海有机化学研究所
推荐引用方式
GB/T 7714
Zhang JT,Wang HY,Zhu W,et al. Solvent-Assisted Electrospray Ionization for Direct Analysis of Various Compounds (Complex) from Low/Nonpolar Solvents and Eluents[J]. Anal. Chem.,2014,86(18):8937-8942.
APA 张骏婷,王昊阳,朱微,蔡婷婷,&郭寅龙.(2014).Solvent-Assisted Electrospray Ionization for Direct Analysis of Various Compounds (Complex) from Low/Nonpolar Solvents and Eluents.Anal. Chem.,86(18),8937-8942.
MLA 张骏婷,et al."Solvent-Assisted Electrospray Ionization for Direct Analysis of Various Compounds (Complex) from Low/Nonpolar Solvents and Eluents".Anal. Chem. 86.18(2014):8937-8942.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
2014456.pdf(791KB)期刊论文作者接受稿开放获取CC BY-NC-SA请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[张骏婷]的文章
[王昊阳]的文章
[朱微]的文章
百度学术
百度学术中相似的文章
[张骏婷]的文章
[王昊阳]的文章
[朱微]的文章
必应学术
必应学术中相似的文章
[张骏婷]的文章
[王昊阳]的文章
[朱微]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。