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学科主题: 生命有机化学
题名: Enzyme inhibition by iminosugars: Analysis and insight into the glycosidase-iminosugar dependency of pH
其他题名: 酶抑制亚氨基糖: 由亚氨基糖的pH值依赖性分析和洞察糖苷酶
作者: LOPEZ OSCAR ; Qing FL(卿凤翎) ; PEDERSEN CHRISTIAN MARCUS ; BOLS MIKAEL
通讯作者: BOLS MIKAEL
刊名: Bioorg. Med. Chem.
发表日期: 2013
卷: 21, 期:16, 页:4755-4761
收录类别: SCI
部门归属: 丹麦哥本哈根大学 ; 中国科学院上海有机化学研究所 ; 西班牙塞维利亚大学
英文摘要: Imino- and azasugar glycosidase inhibitors display pH dependant inhibition reflecting that both the inhibitor and the enzyme active site have groups that change protonation state with pH. With the enzyme having two acidic groups and the inhibitor one basi
语种: 英语
相关网址: 查看原文
WOS记录号: WOS:000322690700003
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/29197
Appears in Collections:中科院有机氟化学重点实验室_期刊论文

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Recommended Citation:
LOPEZ OSCAR,Qing FL,PEDERSEN CHRISTIAN MARCUS,et al. Enzyme inhibition by iminosugars: Analysis and insight into the glycosidase-iminosugar dependency of pH[J]. Bioorg. Med. Chem.,2013,21(16):4755-4761.
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