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SIOC OpenIR  > 中科院天然产物有机化学重点实验室  > 期刊论文
学科主题: 天然产物有机化学
题名: Simple Analogues of Qinghaosu (Artemisinin)
其他题名: 青蒿素简化类似物
作者: Li Y(李云) ; Hao HD(郝宏东) ; Sergio Wittlin ; Wu YK(伍贻康)
通讯作者: 伍贻康
刊名: Chem.-Asian J.
发表日期: 2012
卷: 7, 期:8, 页:1881-1886
收录类别: SCI
部门归属: 中科院上海有机化学研究所; Swiss Tropical and Public Health Institute; University of Basel
英文摘要: A series of 1,2,4-trioxanes were synthesized in which the key peroxy bonds were installed through a molybdenum-catalyzed perhydrolysis of the epoxy rings. A core structure was identified that may serve as a promising lead structure for further investigations because of its high antimalarial activity (comparable to that of artesunate and chloroquine), apparent potential for scale-up and derivatization, and facile monitoring/tracing by using UV light.
语种: 英语
相关网址: 查看原文
WOS记录号: WOS:000306316300020
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内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/28589
Appears in Collections:中科院天然产物有机化学重点实验室_期刊论文

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Recommended Citation:
Li Y,Hao HD,Sergio Wittlin,et al. Simple Analogues of Qinghaosu (Artemisinin)[J]. Chem.-Asian J.,2012,7(8):1881-1886.
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