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Biosynthetic Pathway for High Structural Diversity of a Common Dilactone Core in Antimycin Production
Alternative TitleBiosynthetic Pathway for High Structural Diversity of a Common Dilactone Core in Antimycin Production
Yan Y(闫岩); ZHANG LIHAN; ITO TAKUYA; Ju XD(瞿旭东); ASAKAWA YOSHINORI; AWAKAWA TAKAYOSHI; ABE IKURO; Liu W(刘文)
2012
Source PublicationOrg. Lett.
ISSN1523-7060
Volume14Issue:16Pages:4142-4145
AbstractWe herein report comparative analysis of two versions of the biosynthetic gene clusters of antimycins, a natural product family possessing up to 44 distinct entities. The biosynthetic pathway of antimycins is amenable to the high structural variation of the substrates, supported by successes in heterologous expression of the ant cluster and in fluorine incorporation. The latter facilitated the investigation of the structure-activity relationship into the usually invariable 3-formamidosalicylic acid moiety of the molecules.
Subject Area生命有机化学
Department中科院上海有机化学研究所; 日本东京大学; 日本德岛文理学院
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Indexed BySCI
Language英语
WOS IDWOS:000307526900028
Citation statistics
Document Type期刊论文
Identifierhttp://ir.sioc.ac.cn/handle/331003/28559
Collection生命有机化学国家重点实验室
Corresponding AuthorJu XD(瞿旭东); Liu W(刘文)
Recommended Citation
GB/T 7714
Yan Y,ZHANG LIHAN,ITO TAKUYA,et al. Biosynthetic Pathway for High Structural Diversity of a Common Dilactone Core in Antimycin Production[J]. Org. Lett.,2012,14(16):4142-4145.
APA 闫岩.,ZHANG LIHAN.,ITO TAKUYA.,瞿旭东.,ASAKAWA YOSHINORI.,...&刘文.(2012).Biosynthetic Pathway for High Structural Diversity of a Common Dilactone Core in Antimycin Production.Org. Lett.,14(16),4142-4145.
MLA 闫岩,et al."Biosynthetic Pathway for High Structural Diversity of a Common Dilactone Core in Antimycin Production".Org. Lett. 14.16(2012):4142-4145.
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