中国科学院上海有机化学研究所机构知识库
Advanced  
SIOC OpenIR  > 上海有机化学研究所  > 期刊论文
学科主题: 高分子化学
题名: Film From Peroxidation of an Amino Phospholipid and Its Biocompatibility
其他题名: 磷脂过氧化膜和生物相容性
作者: Wang HJ(王华杰) ; Liu XM(刘新铭) ; Ji LW(季立文) ; Ma DL(马东兰) ; Ren QS(任秋实) ; Wang JY(王瑾晔)
通讯作者: 王瑾晔
刊名: J. Biomed. Mater. Res. Part B
发表日期: 2006
卷: 79B, 期:2, 页:411-419
收录类别: SCI
部门归属: 上海交大; 上海有机所
英文摘要: A new kind of phospholipid product with fluorescence was derived from autoxidation of an aminophospholipid, L-a-phosphatidylethanolamine dilinolcoyl in solid film state. Atomic force microscopy showed that the film product was composed of round and elliptical vesicles with diameters of about 20-45 nm. The product was difficult to dissolve in water and most organic solvents. Fourier transform infrared spectroscopy, solid-state C-13 NMR, and solid-state P-31 NMR indicated that the unsaturated double carbon bond decreased with the reaction, and polymerization within/between phospholipid molecules occurred. Endothelial cells from human vein seeded onto the film showed the highest proliferating activity compared with seeding onto Corning culture plate, glass plate, or phospholipid film with phosphoryl-choline head group, as evaluated by 3-(4,5-timethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay (p < 0.001). The hemocompatibility of the film was also assessed by platelet adhesion and protein adsorption. The results suggest that the product has potential applications as a new biomaterial coating.
语种: 英语
相关网址: 查看原文
WOS记录号: WOS:000241508800026
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/25453
Appears in Collections:上海有机化学研究所_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
2006366.pdf(480KB)----开放获取--View Download

Recommended Citation:
Wang HJ,Liu XM,Ji LW,et al. Film From Peroxidation of an Amino Phospholipid and Its Biocompatibility[J]. J. Biomed. Mater. Res. Part B,2006,79B(2):411-419.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[王华杰]'s Articles
[刘新铭]'s Articles
[季立文]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[王华杰]‘s Articles
[刘新铭]‘s Articles
[季立文]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: 2006366.pdf
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace