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Comparison of cytocompatibility of zein film with other biomaterials and its degradability in vitro
其他题名玉米醇溶蛋白薄膜和其它生物材料细胞相容性比较及其体外降解.
Sun QS(孙庆申); Dong J(董健); Lin ZX(林志新); Yang B(杨斌); Wang JY(王瑾晔)
2005
发表期刊Biopolymers
ISSN0006-3525
卷号78期号:5页码:268-274
摘要Cytocompatibility of particle zein (Pzein) and film zein (Fzein) was evaluated and compared with polyhydroxybutyrate (PHB), its copolymer poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV), polylactic acid (PLA), and collagen, using HL-7702 cells, in terms of cell attachment rate within 3 h, and cell viabilities at 3 and 6 days determined by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) method. The zein degradation test was carried out using collagenase and trypsin, and the degradation product was added to the culture medium at different concentrations in order to examine the concentration-dependent cytotoxic effect. Result: The adhesion rate of the HL-7702 cells on both Pzein and Fzein was higher than that on collagen film. Cell viabilities were higher on both Pzein and Fzein than on films of PLA, PHB, PHBV, and collagen from fish skin. Zein can be degraded by both trypsin and collagenase, and the degradation product can enhance cell viability within a certain range of concentrations. (c) 2005 Wiley Periodicals, Inc.
学科领域高分子化学
部门归属中国科学院上海有机化学研究所; 上海交通大学
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收录类别SCI
语种英语
WOS记录号WOS:000230537000005
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文献类型期刊论文
条目标识符http://ir.sioc.ac.cn/handle/331003/25431
专题上海有机化学研究所
通讯作者Wang JY(王瑾晔)
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GB/T 7714
Sun QS,Dong J,Lin ZX,et al. Comparison of cytocompatibility of zein film with other biomaterials and its degradability in vitro[J]. Biopolymers,2005,78(5):268-274.
APA 孙庆申,董健,林志新,杨斌,&王瑾晔.(2005).Comparison of cytocompatibility of zein film with other biomaterials and its degradability in vitro.Biopolymers,78(5),268-274.
MLA 孙庆申,et al."Comparison of cytocompatibility of zein film with other biomaterials and its degradability in vitro".Biopolymers 78.5(2005):268-274.
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