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学科主题: 高分子化学
题名: Comparison of cytocompatibility of zein film with other biomaterials and its degradability in vitro
其他题名: 玉米醇溶蛋白薄膜和其它生物材料细胞相容性比较及其体外降解.
作者: Sun QS(孙庆申) ; Dong J(董健) ; Lin ZX(林志新) ; Yang B(杨斌) ; Wang JY(王瑾晔)
通讯作者: 王瑾晔
刊名: Biopolymers
发表日期: 2005
卷: 78, 期:5, 页:268-274
收录类别: SCI
部门归属: 中国科学院上海有机化学研究所; 上海交通大学
英文摘要: Cytocompatibility of particle zein (Pzein) and film zein (Fzein) was evaluated and compared with polyhydroxybutyrate (PHB), its copolymer poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV), polylactic acid (PLA), and collagen, using HL-7702 cells, in terms of cell attachment rate within 3 h, and cell viabilities at 3 and 6 days determined by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) method. The zein degradation test was carried out using collagenase and trypsin, and the degradation product was added to the culture medium at different concentrations in order to examine the concentration-dependent cytotoxic effect. Result: The adhesion rate of the HL-7702 cells on both Pzein and Fzein was higher than that on collagen film. Cell viabilities were higher on both Pzein and Fzein than on films of PLA, PHB, PHBV, and collagen from fish skin. Zein can be degraded by both trypsin and collagenase, and the degradation product can enhance cell viability within a certain range of concentrations. (c) 2005 Wiley Periodicals, Inc.
语种: 英语
相关网址: 查看原文
WOS记录号: WOS:000230537000005
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内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/25431
Appears in Collections:上海有机化学研究所_期刊论文

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Recommended Citation:
Sun QS,Dong J,Lin ZX,et al. Comparison of cytocompatibility of zein film with other biomaterials and its degradability in vitro[J]. Biopolymers,2005,78(5):268-274.
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