SIOC OpenIR  > 上海有机化学研究所
Study on the precipitation reaction between baicalin and berberine by HPLC AND LIFE SCIENCES
其他题名高效液相色谱法研究黄芩苷和小檗碱的沉淀反应
Li Y(李奕); Xu X(许旭)
2004
发表期刊J. Chromatogr. B
ISSN1570-0232
卷号810期号:1页码:165-168
摘要The solubility product equilibrium constant for the precipitation between baicalin and berberine was investigated because of the current interest in decocting process of complex prescription of Chinese herbal medicine. HPLC was used for determining two compounds' equilibrium concentrations at different precipitate conditions to calculate thermodynamic constants and study kinetic process. The analysis was performed on a Kromasil C-18 column with TEA-adjusted 0.02 mol/L H3PO4 (pH 4.82)-acetonitrile (75:25) as mobile phase at a flow-rate of 1.0 ml/min, with detection at 254 nm. According to the experiment result, the molar ratio of baicalin and berberine in precipitate is about 1:1. The experimental K-sp values are (1.01 +/- 0.12) x 10(-9) mol(2)/L-2 at 20degreesC in 0.02 mol/L NaH2PO4-Na2HPO4 (pH 4.82), and (3.20 +/- 0.46) x 10(-9) mol(2)/L-2 at 40degreesC in the same buffer. The precipitate reaction is an exothermic process and occurs immediately, even though the precipitate cannot be observed in time because the precipitate is light, yellow, flocculous and suspending in the yellow solution. (C) 2004 Elsevier B.V. All rights reserved.
学科领域分析化学
部门归属中国科学院上海有机化学研究所
URL查看原文
收录类别SCI
语种英语
文献类型期刊论文
条目标识符http://ir.sioc.ac.cn/handle/331003/24723
专题上海有机化学研究所
通讯作者Xu X(许旭)
推荐引用方式
GB/T 7714
Li Y,Xu X. Study on the precipitation reaction between baicalin and berberine by HPLC AND LIFE SCIENCES[J]. J. Chromatogr. B,2004,810(1):165-168.
APA 李奕,&许旭.(2004).Study on the precipitation reaction between baicalin and berberine by HPLC AND LIFE SCIENCES.J. Chromatogr. B,810(1),165-168.
MLA 李奕,et al."Study on the precipitation reaction between baicalin and berberine by HPLC AND LIFE SCIENCES".J. Chromatogr. B 810.1(2004):165-168.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
2004023.pdf(229KB) 开放获取--请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[李奕]的文章
[许旭]的文章
百度学术
百度学术中相似的文章
[李奕]的文章
[许旭]的文章
必应学术
必应学术中相似的文章
[李奕]的文章
[许旭]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。