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学科主题: 生命有机化学
题名: Studies on the physicochemical properties, structure and antitumor activity of polysaccharide YhPS-1 from the root of Cordalis yanhusuo Wang activity; polysaccharide
其他题名: 元胡多糖YhPS-1的理化性质、结构及抗肿瘤活性
作者: Tao YW(陶移文) ; Tian GY(田庚元)
通讯作者: 田庚元
刊名: Chin. J. Chem.
发表日期: 2006-01-01
卷: 24, 期:2, 页:235-239
收录类别: SCI
部门归属: 中科院上海有机所;
英文摘要: A polysaccharide named YhPS-1 was isolated from the root of Cordalis yanhusuo Wang and purified by means of gel-permeation chromatography and ionexchange chromatography. Its physicochemical properties, including monosaccharide composition, carbohydrate content, molecular weight and elemental composition, were determined. The structure of YhPS-1 was elucidated by chemical methods along with H-1 and C-13 NMR spectroscopy ways, such as including two-dimensional HMQC and HMBC experiments. These results show that YhPS-1 possesses a backbone consisting of terminal alpha-Glcp-(1 ->, alpha-Glcp-(1 -> 6), alpha-Glcp-(1 -> 4) and alpha-Glcp-(1 -> 4,6). The bioactive assay showed that it could inhibit the growth of Sarcoma 180 and Lewis pulmonary carcinoma implanted in mice.
语种: 英语
相关网址: 查看原文
内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/22768
Appears in Collections:生命有机化学国家重点实验室_期刊论文

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Recommended Citation:
Tao YW,Tian GY. Studies on the physicochemical properties, structure and antitumor activity of polysaccharide YhPS-1 from the root of Cordalis yanhusuo Wang activity; polysaccharide[J]. Chin. J. Chem.,2006,24(2):235-239.
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