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学科主题: 生命有机化学
题名: Hydroxyethylation of Achryranthes bidentata Polysaccharide and Investigation of Their Antitumor Activity
其他题名: 牛膝多糖的羟乙基化及其衍生物的抗肿瘤活性
作者: Zhang J(张健) ; Tian GY(田庚元)
刊名: J. Carbohydr. Chem.
发表日期: 2005
卷: 24, 期:7, 页:685-696
收录类别: SCI
部门归属: 中国科学院上海有机化学所
英文摘要: The hydroxyethylated Achyranthes bidentata polysaccharides (Abps) were synthesized. The distribution of substituents in these derivatives was studied using HPLC and NMR analysis. The results show that the substituents are not homogeneously distributed along the Abps chain and the reactivity of the hydroxyl groups in the sugar units is OH‐4 ≫ OH‐3>OH‐6≈OH‐1. Bioassay showed that the derivative with a low degree of substitution (DS) was the best choice to inhibit the growth of Lewis pulmonary carcinoma.
语种: 英语
相关网址: 查看原文
WOS记录号: WOS:000233088300002
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内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/22766
Appears in Collections:生命有机化学国家重点实验室_期刊论文

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Recommended Citation:
Zhang J,Tian GY. Hydroxyethylation of Achryranthes bidentata Polysaccharide and Investigation of Their Antitumor Activity[J]. J. Carbohydr. Chem.,2005,24(7):685-696.
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