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学科主题: 生命有机化学
题名: Structural elucidation and antitumor activity of a fructan from cyathula officindlis kuan
其他题名: 一种川膝果聚糖的结构解析及抗肿瘤活性
作者: Chen XM(陈晓明) ; Tian GY(田庚元)
通讯作者: 田庚元
刊名: Carbohydr. Res.
发表日期: 2003-01-01T00:00:00Z
卷: 338, 期:11, 页:1235-1241
收录类别: SCI
部门归属: 中国科学院上海有机化学研究所生命有机国家重点实验室
英文摘要: A fructan named CoPS3 was isolated from Cyathula officindlis Kuan. The structure of CoPS3 was determined by methylation, by the reductive-cleavage method combined with GC-MS analysis, and both 1D and 2D ~1H and ~13C NMR spectroscopy. These results show that CoPS3 is a graminans-type fructan that is comprised of a β--D-fructofuranosyl backbone having residues linked (2→1)-and (2-→6) with branches and an α-D-glucopyranose residue on the nonreducing end of the fructan chain. Each branch is terminated by a β-Fruf residue. Bioassay showed that it could inhibit growth of Lewis pulmonary carcinoma implanted in mice.
语种: 英语
相关网址: 查看原文
内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/22752
Appears in Collections:生命有机化学国家重点实验室_期刊论文

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Recommended Citation:
Chen XM,Tian GY. Structural elucidation and antitumor activity of a fructan from cyathula officindlis kuan[J]. Carbohydr. Res.,2003,338(11):1235-1241.
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