中国科学院上海有机化学研究所机构知识库
Advanced  
SIOC OpenIR  > 上海有机化学研究所  > 期刊论文
学科主题: 生命有机化学
题名: (1H-Benzotriazol-1-yloxy)-N,N-dimethylmethaniminium hexachloroantimonate (BOMI), a novel coupling reagent for solution and solid-phase peptide synthesis
其他题名: 1H-苯骈三唑氧-N-N-二甲基甲亚胺六氯化锑盐,液相和固相肽合成的新型缩合剂
作者: Li P(李鹏) ; Xu JC(徐杰诚)
通讯作者: 徐杰诚
刊名: J. Pept. Res.
发表日期: 2000
卷: 55, 期:2, 页:110-119
收录类别: SCI
部门归属: 中国科学院上海有机化学研究所生命有机国家开放实验室
英文摘要: A HOBt-based immonium-type compound)1H-benzotriazol-1-yloxy)-N-N-dimethyl methaniminium hexachloroantimonate (BOMI), was synthesized and successfully applied to the synthesis of various oligopeptides with good yields. The estimation of racemization and the influence of several reaction parameters such as solvents, bases and temperature wer reactivity of BOMI was much higher than that of HOBt-based phosphonium-and uronium-type coupling reagents. Moreover, its recemization was lower than that of other HOBt-derived coupling reagents. The effectiveness of BOMI was also demonstrated by the synthesis of leu-enkephalin both in solution and in the solid-phase.
语种: 英语
相关网址: 查看原文
WOS记录号: WOS:000085116200003
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/22632
Appears in Collections:上海有机化学研究所_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
2000039.pdf(483KB)----开放获取--View Download

Recommended Citation:
Li P,Xu JC. (1H-Benzotriazol-1-yloxy)-N,N-dimethylmethaniminium hexachloroantimonate (BOMI), a novel coupling reagent for solution and solid-phase peptide synthesis[J]. J. Pept. Res.,2000,55(2):110-119.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[李鹏]'s Articles
[徐杰诚]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[李鹏]‘s Articles
[徐杰诚]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: 2000039.pdf
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace