Tandem addition/cyclization reaction of organozinc reagents to 2-alkynyl aldehydes: Highly efficient regio- and enantioselective synthesis of 1,3-dihydroisobenzofurans and tetrasubstituted furans
其他题名有机锌试剂对2-炔醛的串联加成-环化反应:高效区域选择性合成1,3-二氢苯并呋喃和四取代呋喃
Chai Z(柴卓); Jie ZF(解正峰); Liu XY(刘心源); Zhao G(赵刚); Wang JD(王吉德)
2008
发表期刊J. Org. Chem.
ISSN0022-3263
卷号73期号:7页码:2947-2950
摘要The enantioselective addition of organozinc reagents to some 2-alkynyl benzaldehydes and the subsequent regioselective cyclization step was performed in one pot to form chiral 1,3-dihydroisobenzofurans with good product yields and excellent regio- and enantioselectivities. In the case of 2-alkynyl-cycloalkene aldehydes, tetrasubstituted furans were obtained in good product yields through a 1, 5-hydride shift of the preformed cyclization product.
学科领域金属有机化学
部门归属上海有机所; 新疆大学
URL查看原文
收录类别SCI
语种英语
WOS记录号WOS:000254544800067
引用统计
被引频次:31[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.sioc.ac.cn/handle/331003/20745
专题中科院天然产物有机化学重点实验室
通讯作者Zhao G(赵刚); Wang JD(王吉德)
推荐引用方式
GB/T 7714
Chai Z,Jie ZF,Liu XY,et al. Tandem addition/cyclization reaction of organozinc reagents to 2-alkynyl aldehydes: Highly efficient regio- and enantioselective synthesis of 1,3-dihydroisobenzofurans and tetrasubstituted furans[J]. J. Org. Chem.,2008,73(7):2947-2950.
APA 柴卓,解正峰,刘心源,赵刚,&王吉德.(2008).Tandem addition/cyclization reaction of organozinc reagents to 2-alkynyl aldehydes: Highly efficient regio- and enantioselective synthesis of 1,3-dihydroisobenzofurans and tetrasubstituted furans.J. Org. Chem.,73(7),2947-2950.
MLA 柴卓,et al."Tandem addition/cyclization reaction of organozinc reagents to 2-alkynyl aldehydes: Highly efficient regio- and enantioselective synthesis of 1,3-dihydroisobenzofurans and tetrasubstituted furans".J. Org. Chem. 73.7(2008):2947-2950.
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