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学科主题: 天然产物有机化学
题名: An Aldol Approach to the Total Synthesis of Pamamycin 621 A
其他题名: 由aldol全合成Pamamycin 621A
作者: Ren GB(任国宝) ; Wu YK(伍贻康)
通讯作者: 伍贻康
刊名: Org. Lett.
发表日期: 2009
卷: 11, 期:24, 页:5638-5641
收录类别: SCI
部门归属: 上海有机所
英文摘要: Pamamycin 621 A was synthesized through a convergent route, with the THF rings constructed from Evans aldols in the presence of the chiral auxiliaries without suffering racemization or elimination. The basic amino group was introduced at a late stage through reduction of an azido group with n-Bu3SnH, which also demonstrates for the first time the great potential of this largely forgotten reduction protocol in synthesis of multifunctional substrates.
语种: 英语
相关网址: 查看原文
WOS记录号: WOS:000272461800018
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内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/20433
Appears in Collections:生命有机化学国家重点实验室_期刊论文

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Recommended Citation:
Ren GB,Wu YK. An Aldol Approach to the Total Synthesis of Pamamycin 621 A[J]. Org. Lett.,2009,11(24):5638-5641.
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