中国科学院上海有机化学研究所机构知识库
Advanced  
SIOC OpenIR  > 生命有机化学国家重点实验室  > 期刊论文
学科主题: 生命有机化学
题名: An expeditious enantioselective synthesis of antimycin A(3b)
其他题名: 抗霉素A3b的合成
作者: Wu YK(伍贻康) ; Yang YQ(杨永青)
通讯作者: 伍贻康
刊名: J. Org. Chem.
发表日期: 2006
卷: 71, 期:11, 页:4296-4301
收录类别: SCI
部门归属: 中国科学院上海有机化学研究所
英文摘要: A straightforward enantioselective route to (+)-antimycin A(3b) is presented, which used a TiCl4-mediated asymmetric aldolization to construct C-7/C-8 and BnOH/DMAP to remove the chiral auxiliary with concurrent protection of the carboxylic group, respectively. Closing the dilactone ring was achieved in 62% yield (previously 0.8%, 13.4%, or 20%) in the presence of the C-8 ester functionality. The overall yield (34.5%) was significantly higher than that (0.019-3.6%) of the earlier routes.
语种: 英语
相关网址: 查看原文
WOS记录号: WOS:000237654000034
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/20377
Appears in Collections:生命有机化学国家重点实验室_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
2006215.pdf(101KB)----开放获取--View Download

Recommended Citation:
Wu YK,Yang YQ. An expeditious enantioselective synthesis of antimycin A(3b)[J]. J. Org. Chem.,2006,71(11):4296-4301.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[伍贻康]'s Articles
[杨永青]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[伍贻康]‘s Articles
[杨永青]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: 2006215.pdf
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace