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学科主题: 生命有机化学
题名: Steroid-fullerene adducts from Diels-Alder reactions: characterization and the effect on the activity of Ca^2+-ATPase
其他题名: 由Diels-Alder反应制得的甾体-富勒烯表征及对钙离子ATP酶活性的作用
作者: Li LS(李连生) ; Hu YJ(胡允金) ; Wu YK(伍贻康) ; Jiachang Yue ; Yang FY(杨福玉)
通讯作者: 伍贻康
刊名: J. Chem. Soc.-Perkin Trans. 1
发表日期: 2001-01-01
期: 6, 页:617-621
收录类别: SCI
部门归属: 中国科学院上海有机化学研究所生命有机化学实验室; 中国科学院生物物理所
英文摘要: Two new fullerene steroids (1 and 6)have been prepared by the Diels-Alder reaction of silyloxydienes (2 and 3) with [60]fullerene, followed by hydrolysis of the silyl enol ether under acidic conditions. The isolation, characterization, UV-Vis and CD absorption studies of the adducts are presented. A preliminary study on the effect of 1 on sarcoplasmic reticulum (SR) Ca^2+-ATP ase and survival of human lung adenocarcinoma cancer A549 cells has also been carried out.
语种: 英语
相关网址: 查看原文
内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/20301
Appears in Collections:生命有机化学国家重点实验室_期刊论文

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Recommended Citation:
Li LS,Hu YJ,Wu YK,et al. Steroid-fullerene adducts from Diels-Alder reactions: characterization and the effect on the activity of Ca^2+-ATPase[J]. J. Chem. Soc.-Perkin Trans. 1,2001(6):617-621.
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