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学科主题: 天然产物有机化学
题名: Progress in studies of novel marine bis(indole) alkaloids
其他题名: 新颖海洋双吲哚类生物碱的研究进展
作者: Yang CaiGuang ; Huang H(黄浩) ; Jiang B(姜标)
通讯作者: 姜标
刊名: Curr. Org. Chem.
发表日期: 2004
卷: 8, 期:17, 页:1691-1720
收录类别: SCI
部门归属: 中国科学院上海有机化学研究所金属有机化学实验室
摘要: The marine sponges are the source of a unique group of natural products featuring a novel skeleton, the two indole rings were directed linked by a central heterocyclic moiety. Since topsentin, a bis(indolyl)imidazole, and its analogues were isolated from Topsentia genitrix about a decade ago, scientists have isolated various novel bis(indole) alkaloids from marine organisms especially from deep-water sponges in succession. Over the last 15 years there has been an ever-increasing interest in the biological activity of these molecules. These studies became possible as a result of the scientific development of isolation, purification and total synthesis methods concomitant with the development of fairly simple in vitro tests. This paper offers a general view of the recent progress in the field of novel marine bis(indole) alkaloids, including the topsentins, nortopsentins, rhopaladins, hamacanthins, and dragmacidins family natural products. It focuses on the isolation, structure determination, and total synthesis of these bioactive alkaloids.
语种: 英语
WOS记录号: WOS:000224514700005
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/20205
Appears in Collections:中科院天然产物有机化学重点实验室_期刊论文

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Recommended Citation:
Yang CaiGuang,Huang H,Jiang B. Progress in studies of novel marine bis(indole) alkaloids[J]. Curr. Org. Chem.,2004,8(17):1691-1720.
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