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学科主题: 生命有机化学
题名: Highly enantioselective synthesis of α,α-disubstituted malonamic acids through asymmetric hydrolysis of dinitriles with Rhodococuus sp. CGMCC 0497
其他题名: 用菌株Rhodococuus sp. CGMCC 0497不对称水解丙二腈,继而高对映选择性合成α,α-二取代丙酰胺酸
作者: Wu ZL(吴中柳) ; Li ZY(李祖义)
通讯作者: 李祖义
刊名: Chem. Commun.
发表日期: 2003-01-01
期: 3, 页:386-387
收录类别: SCI
部门归属: 中国科学院上海有机化学研究所生命有机化学实验室
英文摘要: Highly enantioselective hydrolysis of α,α-disubstituted malononitriles by the strain Rhodococuus sp. CGMCC 0497 expressing both nitrile hydratase and amidase activity to give ?-α,α-disubstituted malonamic acids which could be converted to valuable ?-or(S)-alkylated amino acids are reported and the yields of the products are improved remarkabley at a lower reaction temperature.
语种: 英语
相关网址: 查看原文
内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/19739
Appears in Collections:金属有机化学国家重点实验室_期刊论文

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Recommended Citation:
Wu ZL,Li ZY. Highly enantioselective synthesis of α,α-disubstituted malonamic acids through asymmetric hydrolysis of dinitriles with Rhodococuus sp. CGMCC 0497[J]. Chem. Commun.,2003(3):386-387.
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