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学科主题: 生命有机化学
题名: Total synthesis of lobatoside E, a potent antitumor cyclic triterpene saponin
其他题名: 一个潜在的肿瘤药物:环状三萜皂甙Lobatoside E的全合成.
作者: Zhu CS(祝纯生) ; Tang PP(汤平平) ; Yu B(俞飚)
通讯作者: 俞飚
刊名: J. Am. Chem. Soc.
发表日期: 2008
卷: 130, 期:18, 页:5872-5873
收录类别: SCI
部门归属: 上海有机所
英文摘要: Lobatoside E, a novel and complex cyclic triterpene saponin showing potent antitumor activities, has been synthesized for the first time, employing a highly modular approach. The synthesis, starting with oleanolic acid, D-glucose, D-galactose, L-arabinose, and L-rhamnose, requires a total of 73 steps, with the longest linear sequence of 31 steps and in 1.2% overall yield.
语种: 英语
相关网址: 查看原文
WOS记录号: WOS:000255629400021
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内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/19085
Appears in Collections:生命有机化学国家重点实验室_期刊论文

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Recommended Citation:
Zhu CS,Tang PP,Yu B. Total synthesis of lobatoside E, a potent antitumor cyclic triterpene saponin[J]. J. Am. Chem. Soc.,2008,130(18):5872-5873.
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