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学科主题: 生命有机化学
题名: Antibacterial diterpenoids from Sagittaria pygmaea
其他题名: 从Sagittaria pygmaea中的到的有抗菌性的二萜类化合物
作者: Liu XT(刘雪婷) ; SHI YAO ; Yu B(俞飚) ; Williams IAN D ; Sung HERMAN H Y ; ZHANG QIONG ; Liang JINGYU ; Ip NANCY Y ; MIN ZHIDA
通讯作者: MIN ZHIDA
刊名: Planta Med.
发表日期: 2007
卷: 73, 期:1, 页:84-90
收录类别: SCI
部门归属: 上海有机所; 中国药科大学; 香港科技大学
英文摘要: There were five new diterpenoids, 18-beta-D-3,4 -diacetoxyxylopyranosyl-ent-kaur-16-ene (1), 18-beta-L-3,5 -diacetoxyarabinofuranosyl-ent-kaur-16-ene (2), 18-beta-D-3,6 -diacetoxyglucopyranosyl-ent-kaur-16-ene (3), ent-isopimar-8(14),15-dien-19-oic acid (4), and 5 alpha-hydroxy-ent-rosa-15-en-18-oic acid (5), isolated from the whole herb of Sagittaria pygmaea. Their structures and relative configurations were established based on spectroscopic studies, chemical methods, and X-ray crystallographic analysis. Compound 2 exhibited significant antibacterial activity against the oral pathogens, Streptococcus mutans ATCC 25175 and Actinomyces viscosus ATCC 27 044, with MIC values against both pathogens of 15.6 mu g/mL. Compound 3 was active against only A. viscosus ATCC 27044 with an MIC value of 62.5 mu g/mL. Compounds 4 and 5 were active against S. mutans ATCC 25175 and A. viscosus ATCC 27044, with MIC values against both pathogens of 125.0 mu g/mL.
语种: 英语
相关网址: 查看原文
WOS记录号: WOS:000244086400014
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内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/19063
Appears in Collections:生命有机化学国家重点实验室_期刊论文

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Recommended Citation:
Liu XT,SHI YAO,Yu B,et al. Antibacterial diterpenoids from Sagittaria pygmaea[J]. Planta Med.,2007,73(1):84-90.
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