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学科主题: 生命有机化学
题名: Synthesis of OSW saponin analogs with modified sugar residues and their antiproliferative activities
其他题名: 糖端改进的OSW皂甙类似物的合成及其抗类风湿性活性的研究
作者: Tang PP(汤平平) ; F. Mamdani ; X. Hu ; J. O. Liu ; Yu B(俞飚)
通讯作者: 俞飚
刊名: Bioorg. Med. Chem. Lett.
发表日期: 2007
卷: 17, 期:4, 页:1003-1007
收录类别: SCI
部门归属: 上海有机所; 约翰霍普金斯医学院药理系
英文摘要: Eight monosaccharide analogs of the potent antitumor OSW saponins (2-9) were synthesized. One analog, 2-O-acetyl-aL-arabinopyranoside 3, showed antiproliferative activity against the Jurkat cells (IC50 = 0.078 mu M) comparable to that of the disaccharide derivative (1). (c) 2006 Elsevier Ltd. All rights reserved.
语种: 英语
相关网址: 查看原文
WOS记录号: WOS:000244636700029
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内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/19061
Appears in Collections:生命有机化学国家重点实验室_期刊论文

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Recommended Citation:
Tang PP,F. Mamdani,X. Hu,et al. Synthesis of OSW saponin analogs with modified sugar residues and their antiproliferative activities[J]. Bioorg. Med. Chem. Lett.,2007,17(4):1003-1007.
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