A series of benzylic substituted P,N-ligands 1 and 2 have been synthesized. The Pd-complexes of these ligands show high catalytic activity and enantioselectivity in catalyzing the asymmetric Heck reaction. A dramatic switch in enantioselectivity is realiz
Wu WQ,Peng Q,Dong DX,et al. A dramatic switch of enantioselectivity in asymmetric Heck reaction by benzylic substituents of ligands[J]. J. Am. Chem. Soc.,2008,130(30):9717-9725.
