中国科学院上海有机化学研究所机构知识库
Advanced  
SIOC OpenIR  > 中科院有机氟化学重点实验室  > 期刊论文
学科主题: 氟化学 ; 生命有机化学
题名: Synthesis of 2',3'-dideoxy-2 '-monofluoromethyI azanucleosides
其他题名: 2',3'-二去氧-2'-单氟甲基氮杂核苷的合成
作者: Qiu XL(邱小龙) ; Qing FL(卿凤翎)
通讯作者: 卿凤翎
刊名: Bioorg. Med. Chem.
发表日期: 2005-01-01
卷: 13, 期:1, 页:277-283
收录类别: SCI
部门归属: 上海有机所元素有机; 东华大学
英文摘要: (2S,4S)-Methyl-N-tert-butoxycarbonyl-4-monofluoromethylpyroglutamate 6 was synthesized via a key dehydrofluorination followed by hydrogenation. Compound 6 was converted to (5S,3S)-N-benzyloxycarbonyl-5-tert-butyldimethylsilyloxymethyl-3-monoflu oromethyl-2-pyrrolidone 12 over four steps in 62% yield, which was used as a precursor for the synthesis of 2',3'-dideoxy-2'-monofluoromethyl azanucleosides 17-18. (C) 2004 Elsevier Ltd. All rights reserved.
语种: 英语
相关网址: 查看原文
内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/17555
Appears in Collections:中科院有机氟化学重点实验室_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
2005340.pdf(332KB)----开放获取--View Download

Recommended Citation:
Qiu XL,Qing FL. Synthesis of 2',3'-dideoxy-2 '-monofluoromethyI azanucleosides[J]. Bioorg. Med. Chem.,2005,13(1):277-283.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[邱小龙]'s Articles
[卿凤翎]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[邱小龙]‘s Articles
[卿凤翎]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: 2005340.pdf
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace