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学科主题: 氟化学 ; 生命有机化学
题名: Trifluoromethylation of flavonoids and anti-tumor activity of the trifluoromethylated flavonoid derivatives
其他题名: 黄铜的三氟甲基化及三氟甲基黄酮的抗肿瘤活性
作者: Wang CL(王彩玲) ; Meng WD(孟卫东) ; Qing FL(卿凤翎)
通讯作者: 卿凤翎
刊名: Bioorg. Med. Chem. Lett.
发表日期: 2005
卷: 15, 期:20, 页:4456-4458
收录类别: SCI
部门归属: 东华大学; 上海有机所元素有机
英文摘要: 3-Trifluoromethylflavonoid derivatives were prepared for the first time by trifluoromethylation of 3-iodoflavonoid derivatives. Other C ring and B ring trifluoromethylated flavonoid derivatives were also prepared. All the compounds were tested for their effect on the U2OS cell cycle in vitro. Bistrifluoromethylated apigenin derivative 13 showed the strongest activity against the cell growth. (c) 2005 Elsevier Ltd. All rights reserved.
语种: 英语
相关网址: 查看原文
WOS记录号: WOS:000231936700009
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内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/17531
Appears in Collections:中科院有机氟化学重点实验室_期刊论文

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Recommended Citation:
Wang CL,Meng WD,Qing FL. Trifluoromethylation of flavonoids and anti-tumor activity of the trifluoromethylated flavonoid derivatives[J]. Bioorg. Med. Chem. Lett.,2005,15(20):4456-4458.
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