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学科主题: 生命有机化学
题名: Lingshuiol, a novel polyhydroxyl compound with strongly cytotoxic activity from the marine dinoflagellate Amphidinium sp.
其他题名: Lingshuiol,海洋鞭毛藻中的一种具有强细胞毒性的新颖多羟基化合物
作者: Huang XC(黄孝春) ; Zhao D(赵德) ; Guo YW(郭跃伟) ; Wu HM(吴厚铭) ; Wang ZH(王中华) ; Ding JP(丁建平)
通讯作者: 郭跃伟
刊名: Bioorg. Med. Chem. Lett.
发表日期: 2004
卷: 14, 期:12, 页:3117-3120
收录类别: SCI
部门归属: 中国科学院上海有机化学研究所生命有机化学实验室; 中国科学院上海药物所
英文摘要: A novel polyhydroxy compound with a linear carbon-chain, lingshuiol (1), had been isolated from the cultured marine dinoflagellate Amphidinium sp. Its structure was elucidated by extensive analysis of 2D NMR spectral data. Lingshuiol possessed a powerful cytotoxic activity against A-549 and HL-60 cells in vitro with the IC50 of 0.21 and 0.23 muM, respectively. (C) 2004 Elsevier Ltd. All rights reserved.
语种: 英语
相关网址: 查看原文
WOS记录号: WOS:000221776800021
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内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/17353
Appears in Collections:上海有机化学研究所_期刊论文

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Recommended Citation:
Huang XC,Zhao D,Guo YW,et al. Lingshuiol, a novel polyhydroxyl compound with strongly cytotoxic activity from the marine dinoflagellate Amphidinium sp.[J]. Bioorg. Med. Chem. Lett.,2004,14(12):3117-3120.
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