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学科主题: 天然产物有机化学
题名: Characterization of a rhamnogalacturonan and a xyloglucan from nerium indicum and their activities on PC12 pheochromocytoma cells
其他题名: 鼠李-半乳多糖的表征和对PC12细胞活性
作者: Ding K(丁侃) ; Fang JN(芳基年) ; Dong TX(董庭霞) ; Qin GW(秦国伟) ; Wu HM(吴厚铭)
通讯作者: 芳基年
刊名: J. Nat. Prod.
发表日期: 2003-01-01
卷: 66, 期:1, 页:7-10
收录类别: SCI
部门归属: 中国科学院上海药物所; 中国科学院上海有机化学研究所生命有机国家开放实验室
英文摘要: Two polysaccharides. A rhamnogalacturonan (J1) and a xyloglucan (J2). Were isolated and purified from the whole flowers of NeTiunJ indlcuHI and characterized by GC. GC-MS. NMR. And ESMS. The rhamnogalacturonan was found to consist of repeating units of a linear trisaccharide with the structure [→4)-α-GalpA(1→2)α-Rhap(1→4)-α-GalpA(1→4)-]n. while the xyloglucan consisted of repeating units of the trisaccharide. Which was (1→4)-linked β-glucopyranosyl residues as a backbone and substituted at position 6 linked to terminal α-xylopyranose side chains. These two polysaccharides were tested on the -proliferation and differentiation on PCI2 pheochromocytoma cells and found to have effects similar to nerve growth factor (NGF).
语种: 英语
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WOS记录号: WOS:000180623400002
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内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/17323
Appears in Collections:上海有机化学研究所_期刊论文

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Recommended Citation:
Ding K,Fang JN,Dong TX,et al. Characterization of a rhamnogalacturonan and a xyloglucan from nerium indicum and their activities on PC12 pheochromocytoma cells[J]. J. Nat. Prod.,2003,66(1):7-10.
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