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学科主题: 生命有机化学
题名: Isolation and structure of the cytotoxic cycloheptapeptide phakellistatin 13
其他题名: 细胞毒素环七肽 phakellistatin 13的分离和结构
作者: Li WL(李文玲) ; Yi YH(易杨华) ; Wu HM(吴厚铭) ; Xu QZ(徐强芝) ; Tang HF(唐海峰) ; Lin HW(林厚文) ; Wang ZH(王中华)
通讯作者: 易杨华
刊名: J. Nat. Prod.
发表日期: 2003
卷: 66, 期:1, 页:146-148
收录类别: SCI
部门归属: 第二军医大学; 中国科学院上海有机化学研究所生命有机化学实验室
摘要: A new cyclic hepptapeptide phakellistatin 13(1) had been isolated from the sponge phakellia fusca Thiele, collected at Yongxing Island of China. Its structure was elucidated as cyclo-(Pro~1Trp_leu-Thr-Pro~2-Gly-Phe) on the basis of MS, UV, IR, and high-field NMR (600 MHz) analysis. The compound was significantly cytotoxic against the human hepatoma BEL-7404 cell line with an ED^50<10-2 μg/mL
语种: 英语
相关网址: 查看原文
WOS记录号: WOS:000180623400033
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内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/17319
Appears in Collections:上海有机化学研究所_期刊论文

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Recommended Citation:
Li WL,Yi YH,Wu HM,et al. Isolation and structure of the cytotoxic cycloheptapeptide phakellistatin 13[J]. J. Nat. Prod.,2003,66(1):146-148.
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