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学科主题: 生命有机化学
题名: Introridoside-A, a novel cytotoxic glycosphingolipid from the marine spone iotrochota ridley
其他题名: Iotroridoside-A-海绵Iotrochota ridley 中异构具有细胞毒性的新颖糖膦脂质体
作者: Deng SZ(邓松之) ; Tian CL(田春雷) ; Xiao DJ(肖定军) ; Wu HM(吴厚铭)
通讯作者: 邓松之
刊名: Chin. J. Chem.
发表日期: 2001-01-01
卷: 19, 期:4, 页:362-364
收录类别: SCI
部门归属: 广州化学所; 中国科学院上海有机化学研究所生命有机国家开放实验室
英文摘要: A new cytotoxic glycosphingolipid,Iotroridoside-A, was isolated from the marine sponge iotrochota ridley collectd from the South China Sea near hainan Island, China. On the basis of chemical degradation method and IR,MS, ~1H NMR, ~13C NMR and 2D NMR spectrometry, its structure was assigned as 1-O0β-D-glucopyranosyl-2-[(4'Z)-2'-hydroxytetracosene amido]-4-tetradecyl-1,3-4-butntriol. The new compound exhibits strong cytotoxicity against L1210 murine leukemia cells in vitro (ED^50=0.08μg/mL).
语种: 英语
相关网址: 查看原文
内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/17281
Appears in Collections:上海有机化学研究所_期刊论文

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Recommended Citation:
Deng SZ,Tian CL,Xiao DJ,et al. Introridoside-A, a novel cytotoxic glycosphingolipid from the marine spone iotrochota ridley[J]. Chin. J. Chem.,2001,19(4):362-364.
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