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学科主题: 有机化学
题名: New stereoselective synthesis of thiamphenicol and florfenicol from enantiomerically pure cyanohydrin: a chemo-enzymatic approach
其他题名: New stereoselective synthesis of thiamphenicol and florfenicol from enantiomerically pure cyanohydrin: a chemo-enzymatic approach
作者: Lu WY(卢文芽) ; Chen PR(陈沛然) ; Lin GQ(林国强)
通讯作者: 林国强
刊名: Tetrahedron
发表日期: 2008
卷: 64, 期:33, 页:7822-7827
收录类别: SCI
部门归属: 上海有机所; 东华大学
英文摘要: Thiamphenicol and florfenicol have been synthesized stereoselectively from enantiomerically pure 4-methylsulfanyl-mandelonitrile, which was obtained by hydrocyanation reaction of 4-methylsulfanyl-benzaldehyde catalyzed by (R)-hydroxynitrile Iyase of Badamu (Prunus communis L. var. dulcis Borkh, almond from Xinjiang, China). It was found to be a highly effective bio-catalyst for this reaction after an extensive screening. (C) 2008 Elsevier Ltd. All rights reserved.
语种: 英语
相关网址: 查看原文
WOS记录号: WOS:000258081600020
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内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/16671
Appears in Collections:中科院天然产物有机化学重点实验室_期刊论文

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Recommended Citation:
Lu WY,Chen PR,Lin GQ. New stereoselective synthesis of thiamphenicol and florfenicol from enantiomerically pure cyanohydrin: a chemo-enzymatic approach[J]. Tetrahedron,2008,64(33):7822-7827.
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