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学科主题: 有机化学
题名: Synthesis of 1,5-Benzothiazepine Dipeptide Mimetics via Two CuI-Catalyzed Cross Coupling Reactions
其他题名: 经由两次铜催化的偶联反应合成1,5-苯并硫氮杂卓二肽类似物
作者: Gan JG(甘建刚) ; Ma DW(马大为)
通讯作者: 马大为
刊名: Org. Lett.
发表日期: 2009
卷: 11, 期:13, 页:2788-2790
收录类别: SCI
部门归属: 上海有机所
英文摘要: CuI-catalyzed coupling of 4-methylphenyl bromide with amino acids gives N-aryl amino acids, which are converted into linear dipeptides via iodination and condensation with L-Cysteine derived acyl chloride. Cyclization is achieved via a CuI/N,N-dimethylglycine catalyzed intramolecular coupling of aryl iodides with the liberated thiol to afford 1,5-benzothiazepine dipeptide mimetics.
语种: 英语
相关网址: 查看原文
WOS记录号: WOS:000267400100019
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内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/15599
Appears in Collections:生命有机化学国家重点实验室_期刊论文

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Recommended Citation:
Gan JG,Ma DW. Synthesis of 1,5-Benzothiazepine Dipeptide Mimetics via Two CuI-Catalyzed Cross Coupling Reactions[J]. Org. Lett.,2009,11(13):2788-2790.
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