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学科主题: 生命有机化学
题名: An efficient sequential reaction process to polysubstituted indolizidines and quinolizidines and its application to the total synthesis of indolizidine
其他题名: 一个有效的串联反应来制备多取代的indolizidines 和quinolizidines以及在 indolizidine 223A全合成中的应用
作者: Zhu W(朱伟) ; Dong DP(董大鹏) ; Pu XT(蒲晓涛) ; Ma DW(马大为)
通讯作者: 马大为
刊名: Org. Lett.
发表日期: 2005-01-01
卷: 7, 期:4, 页:705-708
收录类别: SCI
部门归属: 上海有机所
英文摘要: [GRAPHICS] The reaction of iodides 1 with delta-chloropropylamines 5 in MeCN assisted with K2CO3 undergoes a sequential S(N)2/Michael addition/S(N)2/S(N)2 reaction process to give polysubstituted indolizidines and quinolizidines. Using this method, indolizidine 223A is synthesized from 2-ethyl-2-hexenoic acid in 12 linear steps and 14.5% overall yield.
语种: 英语
相关网址: 查看原文
内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/15501
Appears in Collections:生命有机化学国家重点实验室_期刊论文

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Recommended Citation:
Zhu W,Dong DP,Pu XT,et al. An efficient sequential reaction process to polysubstituted indolizidines and quinolizidines and its application to the total synthesis of indolizidine[J]. Org. Lett.,2005,7(4):705-708.
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