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学科主题: 生命有机化学
题名: Total synthesis and cytotoxicity studies of a cyclic depsipeptide with proposed structure of palau'amide
其他题名: 环酯肽palau'amide的推测结构的全合成和细胞毒活性研究
作者: Zou B(邹斌) ; Long K(龙凯) ; Ma DW(马大为)
通讯作者: 马大为
刊名: Org. Lett.
发表日期: 2005
卷: 7, 期:19, 页:4237-4240
收录类别: SCI
部门归属: 上海有机所
英文摘要: Total synthesis of a cyclic depsipeptide with proposed structure of palau'amide is achieved, which features a stereoselective elaboration of its 5,7-dihydroxy-2,6-dimethyidodec-2-en-11-ynoic acid unit. The synthetic compound has potent cytotoxicity against three tumor cell lines but different rotation and NMR data compared to those reported for palau'amide, which implies that its conformation is close to that of palau'amide but that some stereochemistry in palau'amide was misassigned.
语种: 英语
相关网址: 查看原文
WOS记录号: WOS:000231858100044
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内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/15481
Appears in Collections:生命有机化学国家重点实验室_期刊论文

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Recommended Citation:
Zou B,Long K,Ma DW. Total synthesis and cytotoxicity studies of a cyclic depsipeptide with proposed structure of palau'amide[J]. Org. Lett.,2005,7(19):4237-4240.
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