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学科主题: 生命有机化学
题名: Sythesis of an oxazoline analogue of apratoxin A
其他题名: Apratoxin A 的噁唑啉类似物的合成
作者: Zou B(邹斌) ; Wei JJ(魏景军) ; Cai GR(蔡国荣) ; Ma DW(马大为)
通讯作者: 马大为
刊名: Org. Lett.
发表日期: 2003-01-01
卷: 5, 期:19, 页:3503-3506
收录类别: SCI
部门归属: 中国科学院上海有机化学研究所生命有机国家开放实验室
英文摘要: Michael addition of Me^2Cu(CN)Li^2 to α,β-unsaurated lactone 7 derived from-β-hydroxyl ketone 5 provides lactone 8, which is converted to alcohol 11 using oppolzer's methodology as the key step. Connection of 11 with the L-proline moiety and subsequent installation of an oxazoline ring affords 16, which is coupled with tripeptide 21; subsequent macrocyclization then furnishes 4, an oxazoline analogue of apratoxin A.
语种: 英语
相关网址: 查看原文
内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/15445
Appears in Collections:生命有机化学国家重点实验室_期刊论文

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Recommended Citation:
Zou B,Wei JJ,Cai GR,et al. Sythesis of an oxazoline analogue of apratoxin A[J]. Org. Lett.,2003,5(19):3503-3506.
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