中国科学院上海有机化学研究所机构知识库
Advanced  
SIOC OpenIR  > 生命有机化学国家重点实验室  > 期刊论文
学科主题: 生命有机化学
题名: Polyether mimics of naturally occurring cytotoxic annonaceous acetogenins
其他题名: 天然蕃荔枝内脂的具细胞毒性的多醚类模拟物
作者: Yao ZJ(姚祝军) ; Wu HP(吴海平) ; Wu YL(吴毓林)
通讯作者: 吴毓林
刊名: J. Med. Chem.
发表日期: 2000-01-01T00:00:00Z
卷: 43, 页:2484-2487
收录类别: SCI
部门归属: 中国科学院上海有机化学研究所生命有机国家开放实验室; 上海交通大学
英文摘要: On the basis of the ionophore model, polyether analogues 4 and 6 were designed and synthesized to mimic the naturally occurring annonaceous acetogenins corossolin (2) and bullatin (5). Which were discovered as members of a large family of novel polyketides with cytotoxicity, antitumoral and other biological activities since 1982. The preliminary screening shows that they have compatible cytotoxicity with the corresponding natural annonaceous acetogenins. These results open a potential way to find more active antitumor agents with simpligied structures based on natural annonaceous acetogenins.
语种: 英语
相关网址: 查看原文
内容类型: 期刊论文
URI标识: http://ir.sioc.ac.cn/handle/331003/13972
Appears in Collections:生命有机化学国家重点实验室_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
2000048.pdf(245KB)----开放获取--View Download

Recommended Citation:
Yao ZJ,Wu HP,Wu YL. Polyether mimics of naturally occurring cytotoxic annonaceous acetogenins[J]. J. Med. Chem.,2000,43:2484-2487.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[姚祝军]'s Articles
[吴海平]'s Articles
[吴毓林]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[姚祝军]‘s Articles
[吴海平]‘s Articles
[吴毓林]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: 2000048.pdf
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace